Fri Apr 04 2025

21 articles - From Friday Mar 28 2025 to Friday Apr 04 2025

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Inflamm Bowel Dis

Artificial Intelligence for Classification of Endoscopic Severity of Inflammatory Bowel Disease: A Systematic Review and Critical Appraisal.

Multiple AI models have demonstrated the potential for clinical translation for ulcerative colitis. Research concerning the endoscopic severity assessment of Crohn's disease is limited and should be further explored. More rigorous external validation of AI models and increased transparency of data and codes are needed to improve the quality of AI studies.

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Pancreatology

Effect of selective COX-2 inhibitors and non-selective non-steroidal anti-inflammatory drugs on severity of acute pancreatitis: A systematic review and meta-analysis.

Selective COX-2 inhibitors potentially mitigate disease severity and shorten hospitalization in patients with AP, while non-selective NSAIDs lack this benefit. Confirmatory large-scale RCTs are warranted to validate these findings.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Associations between Placental Parameters and Childhood BMI Trajectories from Birth to 9 Years of Age in the Lifeways Cross-Generation Cohort.

Higher placental weight was initially associated with higher offspring BMI in a non-sex-specific manner, but its influence diminishes by age nine. The influence of maternal BMI on offspring BMI at age nine may reflect the cumulative impact of maternal BMI on offspring BMI trajectories as children approach pre-adolescence. Future research should include larger, more diverse populations to better understand these associations.

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FOOD COMPASS SCORE-10: VALIDATION OF A METHOD FOR EVALUATING THE HEALTHFULNESS OF FOODS AND BEVERAGES USING INGREDIENT LIST INFORMATION.

FCS-10 offers a practical approach for estimating the healthfulness of diverse packaged foods and beverages using readily available label data while maintaining the strengths of the original system.

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Inflamm Bowel Dis

The Impact of Endoscopic Healing on Disease-Related Outcomes in Patients With Ulcerative Proctitis.

UP patients with EH had less IBD-related healthcare utilization, fewer IBD-related complications, and were less likely to escalate therapy after relapse than patients without EH. Using a treatment target of EH may therefore be desirable in UP.

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J Crohns Colitis

Corticosteroid-Sparing Effects of Risankizumab Efficacy and Safety in Patients With Moderately to Severely Active Ulcerative Colitis.

Efficacy of RZB induction therapy was independent of corticosteroid use, with high rates of corticosteroid-free outcomes observed in the overall population and among patients with baseline corticosteroid use, reaffirming the potential of RZB to serve as a corticosteroid-sparing therapy for patients with ulcerative colitis.

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Fidaxomicin for Clostridioides difficile infection in patients with inflammatory bowel disease: a multicentre retrospective cohort study.

Fidaxomicin was effective and safe in IBD patients with CDI, with greater effectiveness in CDI-naïve patients, potentially influencing short-term IBD outcomes.

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Patient-donor similarity and donor-derived species contribute to the outcome of faecal microbiota transplantation for ulcerative colitis.

This study provides important insights for developing patient-tailored FMT-based therapies for UC.

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Real-world Effectiveness of Ustekinumab Versus Anti-TNF or Vedolizumab in Ulcerative Colitis: Induction and 12-Month Maintenance Results from the Prospective, Observational RUN-UC Study.

In the prospective RUN-UC study with PS-weighted groups, UST showed higher treatment persistence but no significant difference in maintenance effectiveness compared to anti-TNF or VDZ in UC.

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The mediating role of psychological inflexibility on internalised stigma and patient outcomes in a sample of adults with inflammatory bowel disease.

Psychological inflexibility significantly impacts quality of life in individuals with internalised stigma related to IBD and mediates the relationship between internalised stigma and patient outcomes. Increasing psychological flexibility in adults with IBD may reduce distress and enhance quality of life. Longitudinal studies and trials of psychological interventions targeting psychological flexibility warrant exploration.

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Liver Transpl

Center-Level variations are associated with disparate waitlist mortality and probability of liver transplant in MELD 35 and greater patients.

For patients receiving an LT, post-transplant survival did not differ among the groups, though high-risk centers transplanted far less high-acuity patients. These variations may indicate that certain centers are associated with substantially decreased waitlist mortality for the highest acuity patients without corresponding decreases in post-transplant survival.

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Geospatial analysis of liver donation after death by drug intoxication.

Assessing liver donation following drug intoxication allows for targeted efforts to increase donations in regions with the greatest potential for improvement.

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Reduction of hepatectomy times in dutch organ procurement teams.

In conclusion, a significant and relevant reduction in hepatectomy time was achieved with this intervention program. We advocate a similar procurement intervention plan in any organ donation program independent of their context.

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Pancreas

Using Animations to Educate Children and Caregivers on Pediatric Pancreatitis - Assessing the Impact and Utilization of the National Pancreas Foundation's Pediatric Animated Pancreas Patient.

The average yearly view/incidence for Pediatric modules was 1.8 times higher than for adult modules, with the majority reporting that they learned new information. The popularity of the Pediatric modules confirms that online educational content is highly accessible and successful in educating patients and caregivers about Pediatric pancreatitis and confirms the need to continue to utilize these educational modules now and in the future.

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Pancreatology

Metallic trace elements in pancreatic tissue are associated with higher risk of pancreatic adenocarcinoma - METAPANDA study.

This pilot study presents unpublished information about a large set of MTE in pancreatic tissues, confirming the possible involvement of arsenic and lead in PDAC onset and highlighting the potential role of antimony and thallium which have never been implicated before.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Inflamm Bowel Dis

Enhancing Surgical Decision-Making in PSC-IBD: A Call for Comprehensive Long-Term Outcomes and Standardized Follow-Up Protocols.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

J Crohns Colitis

Correction to: P0722 Efficacy and Safety of Risankizumab in Patients With Moderate to Severe Crohn's Disease: Results From the One-Year SEQUENCE Open-Label Long-Term Extension.

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Liver Transpl

Can we safely scale RAPID in transplant oncology?

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Robotic living donor hepatectomy: Redefining global standards in living donor liver transplant.

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Split liver transplantation and allocation policy: an uncertain connection.

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Three Problems, Two Viruses, and One Man with a Vision and Voice: Larry Kramer, Medical Activist.

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Letters&Replies

Letters to the editors and authors’ replies